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From flab to fab : transforming surgical waste into an effective bioactive coating material

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : From flab to fab : transforming surgical waste into an effective bioactive coating material
นักวิจัย : Luo, Baiwen , Yuan, Shaojun , Foo, Selin Ee Min , Wong, Marcus Thien Chong , Lim, Thiam Chye , Tan, Nguan Soon , Choong, Cleo
คำค้น : DRNTU::Science::Medicine::Biomedical engineering , DRNTU::Engineering::Materials::Biomaterials
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : Luo, B., Yuan, S., Foo, S. E. M., Wong, M. T. C., Lim, T. C., Tan, N. S., et al. (2015). From flab to fab : transforming surgical waste into an effective bioactive coating material. Advanced healthcare materials, 4(4), 613-620. , 2192-2640 , http://hdl.handle.net/10220/25341 , http://dx.doi.org/10.1002/adhm.201400514
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Advanced healthcare materials
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Cellular events are regulated by the interaction between integrin receptors in the cell membrane and the extracellular matrix (ECM). Hence, ECM, as a material, can potentially play an instructive role in cell–material interactions. Currently, adipose tissue in the form of lipoaspirate is often discarded. Here, it is demonstrated how our chemical-free decellularization method could be used to obtain ECM from human lipoaspirate waste material. These investigations show that the main biological components are retained in the lipoaspirate-derived ECM (LpECM) material and that this LpECM material could subsequently be used as a coating material to confer bioactivity to an otherwise inert biodegradable material (i.e., polycaprolactone). Overall, lipoaspirate material, a complex blend of endogenous proteins, is effectively used a bioactive coating material. This work is an important stepping-stone towards the development of biohybrid scaffolds that contain cellular benefits without requiring the use of additional biologics based on commonly discarded lipoaspirate material.

บรรณานุกรม :
Luo, Baiwen , Yuan, Shaojun , Foo, Selin Ee Min , Wong, Marcus Thien Chong , Lim, Thiam Chye , Tan, Nguan Soon , Choong, Cleo . (2557). From flab to fab : transforming surgical waste into an effective bioactive coating material.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Luo, Baiwen , Yuan, Shaojun , Foo, Selin Ee Min , Wong, Marcus Thien Chong , Lim, Thiam Chye , Tan, Nguan Soon , Choong, Cleo . 2557. "From flab to fab : transforming surgical waste into an effective bioactive coating material".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Luo, Baiwen , Yuan, Shaojun , Foo, Selin Ee Min , Wong, Marcus Thien Chong , Lim, Thiam Chye , Tan, Nguan Soon , Choong, Cleo . "From flab to fab : transforming surgical waste into an effective bioactive coating material."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print.
Luo, Baiwen , Yuan, Shaojun , Foo, Selin Ee Min , Wong, Marcus Thien Chong , Lim, Thiam Chye , Tan, Nguan Soon , Choong, Cleo . From flab to fab : transforming surgical waste into an effective bioactive coating material. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.