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Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium

หน่วยงาน Central Queensland University, Australia

รายละเอียด

ชื่อเรื่อง : Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium
นักวิจัย : Bernard, Catherine. , Froscio, Suzanne. , Campbell, Rebecca. , Monis, Paul T. , Humpage, Andrew. , Fabbro, Larelle D.
คำค้น : Applied research. , 960506 Ecosystem Assessment and Management of Fresh, Ground and Surface Water Environments. , 960912 Urban and Industrial Water Management. , 920499 Public Health (excl. Specific Population Health) not elsewhere classified. , 050205 Environmental Management. , 060701 Phycology (incl. Marine Grasses) , 111705 Environmental and Occupational Health and Safety. , Cyanobacteria. , Algology. , Environmental management. , Freshwater ecology. , ATP -- Cyanobacteria -- Cylindrospermopsin -- Freshwater -- Geitlerinema -- Limnothrix -- Oscillatoriales -- Protein inhibition assay -- Pseudanabaenacea -- Toxic response , Journal Article. Refereed, Scholarly Journal
หน่วยงาน : Central Queensland University, Australia
ผู้ร่วมงาน : -
ปีพิมพ์ : 2554
อ้างอิง : http://hdl.cqu.edu.au/10018/43993 , http://dx.doi.org/10.1002/tox.20552
ที่มา : Bernard, C, Froscio, S, Campbell, R, Monis, P, Humpage, A & Fabbro, L 2011, 'Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium, Environmental Toxicology, vol. 26, no. 3, pp. 260-270, http://dx.doi.org/10.1002/tox.20552
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Environmental toxicology. New York, N.Y. : John Wiley & Sons, Inc, 2011. Vol. 26, no. 3, (2011), p. 260-270 11 pages Refereed 1522-7278 1520-4081 (online) , ACQUIRE [electronic resource] : Central Queensland University Institutional Repository.
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The presence of a toxic strain of a fine filamentous cyanobacterium belonging to the Oscillatorialean family Pseudanabaenacea was detected during a survey of cyanobacterial taxa associated with the presence of cylindrospermopsin in dams in Central Queensland (Australia). The strain, AC0243, was isolated and cultured, its genomic DNA extracted and 16S RNA gene sequenced. Phylogenetic analysis placed AC0243 with Limnothrix species, although this genus appears polyphyletic. Moreover, not all morphological characters are consistent with this genus but more closely fit the description of Geitlerinema unigranulatum (R.N. Singh) Komarek and Azevedo. The potential toxic effects of AC0243 extract were assessed chemically and biologically. Cell free protein synthesis was inhibited by the extract. Exposure of Vero cells to the extract resulted in a significant reduction in cellular ATP levels following 24–72 h incubation.The presence of cylindrospermopsin was excluded based on the nature of responses obtained in cell and cell-free assays; in addition, (i) it could not be detected by HPLC, LC-MS, or immunological assay, and (ii) no genes currently associated with the production of cylindrospermopsin were found in the genome.Other known cyanobacterial toxins were not detected. The apparent novelty of this toxin is discussed.

บรรณานุกรม :
Bernard, Catherine. , Froscio, Suzanne. , Campbell, Rebecca. , Monis, Paul T. , Humpage, Andrew. , Fabbro, Larelle D. . (2554). Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium.
    กรุงเทพมหานคร : Central Queensland University, Australia.
Bernard, Catherine. , Froscio, Suzanne. , Campbell, Rebecca. , Monis, Paul T. , Humpage, Andrew. , Fabbro, Larelle D. . 2554. "Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium".
    กรุงเทพมหานคร : Central Queensland University, Australia.
Bernard, Catherine. , Froscio, Suzanne. , Campbell, Rebecca. , Monis, Paul T. , Humpage, Andrew. , Fabbro, Larelle D. . "Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium."
    กรุงเทพมหานคร : Central Queensland University, Australia, 2554. Print.
Bernard, Catherine. , Froscio, Suzanne. , Campbell, Rebecca. , Monis, Paul T. , Humpage, Andrew. , Fabbro, Larelle D. . Novel toxic effects associated with a tropical Limnothrix/Geitlerinema-like cyanobacterium. กรุงเทพมหานคร : Central Queensland University, Australia; 2554.