ridm@nrct.go.th   ระบบคลังข้อมูลงานวิจัยไทย   รายการโปรดที่คุณเลือกไว้

Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation
นักวิจัย : Lee, Mian Rong , Phang, In Yee , Cui, Yan , Lee, Yih Hong , Ling, Xing Yi
คำค้น : DRNTU::Science::Physics
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : Lee, M. R., Phang, I. Y., Cui, Y., Lee, Y. H., & Ling, X. Y. (2015). Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation. Small, 11(6), 740-748. , 1613-6810 , http://hdl.handle.net/10220/25174 , http://dx.doi.org/10.1002/smll.201401343
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Small
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The ability to shape-shift in response to a stimulus increases an organism's survivability in nature. Similarly, man-made dynamic and responsive “smart” microtechnology is crucial for the advancement of human technology. Here, 10–30 μm shape-changing 3D BSA protein hydrogel microstructures are fabricated with dynamic, quantitative, directional, and angle-resolved bending via two-photon photolithography. The controlled directional responsiveness is achieved by spatially controlling the cross-linking density of BSA at a nanometer lengthscale. Atomic force microscopy measurements of Young's moduli of structures indicate that increasing the laser writing distance at the z-axis from 100–500 nm decreases the modulus of the structure. Hence, through nanoscale modulation of the laser writing z-layer distance at the nanoscale, control over the cross-linking density is possible, allowing for the swelling extent of the microstructures to be quantified and controlled with high precision. This method of segmented moduli is applied within a single microstructure for the design of shape-shifting microstructures that exhibit stimulus-induced chirality, as well as for the fabrication of a free-standing 3D microtrap which is able to open and close in response to a pH change.

บรรณานุกรม :
Lee, Mian Rong , Phang, In Yee , Cui, Yan , Lee, Yih Hong , Ling, Xing Yi . (2557). Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Lee, Mian Rong , Phang, In Yee , Cui, Yan , Lee, Yih Hong , Ling, Xing Yi . 2557. "Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Lee, Mian Rong , Phang, In Yee , Cui, Yan , Lee, Yih Hong , Ling, Xing Yi . "Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print.
Lee, Mian Rong , Phang, In Yee , Cui, Yan , Lee, Yih Hong , Ling, Xing Yi . Shape-shifting 3D protein microstructures with programmable directionality via quantitative nanoscale stiffness modulation. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.