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Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: A pilot randomized controlled trial

หน่วยงาน สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์

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ชื่อเรื่อง : Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: A pilot randomized controlled trial
นักวิจัย : Plaiwan Suttanon , Hill, Keith D. , Said, Catherine M. , Williams, Susan B. , Byrne, Karin N. , LoGiudice, Dina C. , Lautenschlager, Nicola T. , Dodd, Karen J.
คำค้น : Alzheimer's disease , Balance and strengthening exercise , Falls risk , Randomized controlled trial
หน่วยงาน : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Clinical Rehabilitation. 27, 5 (2013) pp. 427-438 , 0269-2155 , http://dspace.library.tu.ac.th/handle/3517/6762
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Objective: To evaluate the feasibility and safety of a home-based exercise programme for people with Alzheimer's disease, and to provide preliminary evidence of programme effectiveness in improving balance and mobility and reducing falls risk. Design: A randomized controlled trial. Setting: Community. Participants: Forty people with mild to moderate Alzheimer's disease (mean age 81.9, SD 5.72; 62.5% female). Interventions: Participants were randomized to a six-month home-based individually tailored balance, strengthening and walking exercise programme (physiotherapist) or a six-month home-based education programme (control) (occupational therapist). Both programmes provided six home-visits and five follow-up phone calls. Main measures: Balance, mobility, falls and falls risk were measured at baseline and programme completion. Intention-to-treat analysis using a generalized linear model with group allocation as a predictor variable was performed to evaluate programme effectiveness. Feasibility and adverse events were systematically recorded at each contact. Results: Fifty-eight per cent of the exercise group finished the programme, completing an average of 83% of prescribed sessions, with no adverse events reported. Functional Reach improved significantly (P = 0.002) in the exercise group (mean (SD), 2.28 (4.36)) compared to the control group (-2.99 (4.87)). Significant improvement was also observed for the Falls Risk for Older People - Community score (P = 0.008) and trends for improvement on several other balance, mobility, falls and falls risk measures for the exercise group compared to the control group. Conclusions: The exercise programme was feasible and safe and may help improve balance and mobility performance and reduce falls risk in people with Alzheimer's disease. © The Author(s) 2012.

บรรณานุกรม :
Plaiwan Suttanon , Hill, Keith D. , Said, Catherine M. , Williams, Susan B. , Byrne, Karin N. , LoGiudice, Dina C. , Lautenschlager, Nicola T. , Dodd, Karen J. . (2556). Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: A pilot randomized controlled trial.
    กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ .
Plaiwan Suttanon , Hill, Keith D. , Said, Catherine M. , Williams, Susan B. , Byrne, Karin N. , LoGiudice, Dina C. , Lautenschlager, Nicola T. , Dodd, Karen J. . 2556. "Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: A pilot randomized controlled trial".
    กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ .
Plaiwan Suttanon , Hill, Keith D. , Said, Catherine M. , Williams, Susan B. , Byrne, Karin N. , LoGiudice, Dina C. , Lautenschlager, Nicola T. , Dodd, Karen J. . "Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: A pilot randomized controlled trial."
    กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ , 2556. Print.
Plaiwan Suttanon , Hill, Keith D. , Said, Catherine M. , Williams, Susan B. , Byrne, Karin N. , LoGiudice, Dina C. , Lautenschlager, Nicola T. , Dodd, Karen J. . Feasibility, safety and preliminary evidence of the effectiveness of a home-based exercise programme for older people with Alzheimer's disease: A pilot randomized controlled trial. กรุงเทพมหานคร : สถาบันวิจัยและให้คำปรึกษาแห่ง มหาวิทยาลัยธรรมศาสตร์ ; 2556.