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Comparison of efficacy between 20 MG propofol and 3 MG nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients

หน่วยงาน จุฬาลงกรณ์มหาวิทยาลัย

รายละเอียด

ชื่อเรื่อง : Comparison of efficacy between 20 MG propofol and 3 MG nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients
นักวิจัย : Somrat Charuluxananan, 1959-
คำค้น : Propofol , Nalbuphine , Morphine , Intrathecal
หน่วยงาน : จุฬาลงกรณ์มหาวิทยาลัย
ผู้ร่วมงาน : Oranuch Kyokong , Somrat Lertmaharit , Chulalongkorn University. Faculty of Medicine
ปีพิมพ์ : 2542
อ้างอิง : 9743334955 , http://cuir.car.chula.ac.th/handle/123456789/4089
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Thesis (M.Sc.)--Chulalongkorn University, 1999

Objective : To compare the efficacy of 20 mg propofol and 3 mg nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients. Design : Randomized double-bline controlled trial. Setting : Chulalongkorn University Hospital which is the tertiary care center. Methods : One hundred eighty one parturients who developed moderate to severe pruritus caused by intrathecal morphine were randomly allocate into 2 groups with simple randomization. One group received 20 mg propofol while the other one received 3 mg nalbuphine. The improvement of pruritus and other adverse effects were determined at 10 minute after study drug administration. Results : The treatment success rate was higher in nalbuphine group than in propofol group (83.5% VS 61.1%, p = 0.0008). Among the successfully treated patients, the recurrence rates of moderate to severe pruritus within 4 hours were not significantly different (nalbuphine 9.2% VS propofol 7.3%, p= 0.7603). Other side effects such as decreased analgesia, decreased nausea, vomiting, increased sedation, pain on injection, dizziness were not significantly different. Conclusion : Three milligrams of nalbuphine is more efficacious than 20 mg propofol in treatment of intrathecal morphine induced pruritus in caesarean-section patients with few and minor side effects.

บรรณานุกรม :
Somrat Charuluxananan, 1959- . (2542). Comparison of efficacy between 20 MG propofol and 3 MG nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients.
    กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย.
Somrat Charuluxananan, 1959- . 2542. "Comparison of efficacy between 20 MG propofol and 3 MG nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients".
    กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย.
Somrat Charuluxananan, 1959- . "Comparison of efficacy between 20 MG propofol and 3 MG nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients."
    กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย, 2542. Print.
Somrat Charuluxananan, 1959- . Comparison of efficacy between 20 MG propofol and 3 MG nalbuphine in treatment of intrathecal morphine induced pruritus in caesarean-section patients. กรุงเทพมหานคร : จุฬาลงกรณ์มหาวิทยาลัย; 2542.