ชื่อเรื่อง | : | Multiplexed biomolecular detection based on single nanoparticles immobilized on pneumatically controlled microfluidic chip |
นักวิจัย | : | Wu, Bo , Chen, Li-Chan , Huang, Youju , Zhang, Yiming , Kang, Yuejun , Kim, Dong-Hwan |
คำค้น | : | DRNTU::Engineering::Chemical engineering::Biochemical engineering |
หน่วยงาน | : | Nanyang Technological University, Singapore |
ผู้ร่วมงาน | : | - |
ปีพิมพ์ | : | 2557 |
อ้างอิง | : | Wu, B., Chen, L. C., Huang, Y., Zhang, Y., Kang, Y., & Kim, D. H. (2014). Multiplexed biomolecular detection based on single nanoparticles immobilized on pneumatically controlled microfluidic chip. Plasmonics, 9(4), 801-807. , http://hdl.handle.net/10220/24981 , http://dx.doi.org/10.1007/s11468-013-9661-4 |
ที่มา | : | - |
ความเชี่ยวชาญ | : | - |
ความสัมพันธ์ | : | Plasmonics |
ขอบเขตของเนื้อหา | : | - |
บทคัดย่อ/คำอธิบาย | : | A microfluidic chip integrated with pneumatically controlled valves was developed for multiplexed biomolecular detection via localized surface plasmonic resonance (LSPR) of single gold nanorod. The cost-effective microfluidic chip was assembled by polydimethylsiloxane (PDMS) layers and glass substrates with a precisely controlled thickness. The thin and flat microfluidic chip fitted the narrow space of dark-field microscopy and enabled the recording of single nanoparticle LSPR responses. Aptamer-antigen-antibody sandwiched detection scheme was utilized to enhance the LSPR responses for label-free biomolecular detection. This microfluidic chip successfully demonstrated the multiplexed detection of three independent analytes (PSA, IgE, and thrombin). |
บรรณานุกรม | : |
Wu, Bo , Chen, Li-Chan , Huang, Youju , Zhang, Yiming , Kang, Yuejun , Kim, Dong-Hwan . (2557). Multiplexed biomolecular detection based on single nanoparticles immobilized on pneumatically controlled microfluidic chip.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Wu, Bo , Chen, Li-Chan , Huang, Youju , Zhang, Yiming , Kang, Yuejun , Kim, Dong-Hwan . 2557. "Multiplexed biomolecular detection based on single nanoparticles immobilized on pneumatically controlled microfluidic chip".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. Wu, Bo , Chen, Li-Chan , Huang, Youju , Zhang, Yiming , Kang, Yuejun , Kim, Dong-Hwan . "Multiplexed biomolecular detection based on single nanoparticles immobilized on pneumatically controlled microfluidic chip."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print. Wu, Bo , Chen, Li-Chan , Huang, Youju , Zhang, Yiming , Kang, Yuejun , Kim, Dong-Hwan . Multiplexed biomolecular detection based on single nanoparticles immobilized on pneumatically controlled microfluidic chip. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.
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