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Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents
นักวิจัย : Liu, Xiao Li , Choo, Eugene Shi Guang , Ahmed, Anansa S. , Zhao, Ling Yun , Yang, Yong , Ramanujan, Raju V. , Xue, Jun Min , Fan, Dai Di , Fan, Hai Ming , Ding, Jun
คำค้น : DRNTU::Engineering::Materials::Organic/Polymer electronics
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : Liu, X. L., Choo, E. S. G., Ahmed, A. S., Zhao, L. Y., Yang, Y., Ramanujan, R. V., et al. (2013). Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents. Journal of materials chemistry B, 2(1), 120-128. , 2050-750X , http://hdl.handle.net/10220/24427 , http://dx.doi.org/10.1039/c3tb21146k
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of materials chemistry B
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Uniform magnetic nanoparticle-loaded polymer nanospheres with different loading contents of manganese ferrite nanoparticles were successfully synthesized using a flexible emulsion process. The MnFe2O4-loaded polymer nanospheres displayed an excellent dispersibility in both water and phosphate buffer saline. The effect of loading ratio and size of MnFe2O4 nanoparticles within the nanospheres on the specific absorption rate (SAR) under an alternating magnetic field was investigated. Our results indicate that a large size (here 18 nm) and a low loading ratio are preferable for a high SAR. For a smaller particle size (6 nm), the low loading ratio did not result in an enhancement of the SAR value, while a very low SAR value is expected for 6 nm. In addition, the SAR of low-content MnFe2O4 (18 nm)-loaded polymer nanospheres in the agarose gel which is simulated for in vivo environment is the highest among the samples and does not change substantially in physiological environments. This differs largely from the behaviour of singly dispersed nanoparticles. Our results have paved the way for the design of MnFe2O4-loaded polymer nanospheres as magnetic hyperthermia agents for in vivo bio-applications.

บรรณานุกรม :
Liu, Xiao Li , Choo, Eugene Shi Guang , Ahmed, Anansa S. , Zhao, Ling Yun , Yang, Yong , Ramanujan, Raju V. , Xue, Jun Min , Fan, Dai Di , Fan, Hai Ming , Ding, Jun . (2557). Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Liu, Xiao Li , Choo, Eugene Shi Guang , Ahmed, Anansa S. , Zhao, Ling Yun , Yang, Yong , Ramanujan, Raju V. , Xue, Jun Min , Fan, Dai Di , Fan, Hai Ming , Ding, Jun . 2557. "Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Liu, Xiao Li , Choo, Eugene Shi Guang , Ahmed, Anansa S. , Zhao, Ling Yun , Yang, Yong , Ramanujan, Raju V. , Xue, Jun Min , Fan, Dai Di , Fan, Hai Ming , Ding, Jun . "Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print.
Liu, Xiao Li , Choo, Eugene Shi Guang , Ahmed, Anansa S. , Zhao, Ling Yun , Yang, Yong , Ramanujan, Raju V. , Xue, Jun Min , Fan, Dai Di , Fan, Hai Ming , Ding, Jun . Magnetic nanoparticle-loaded polymer nanospheres as magnetic hyperthermia agents. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.