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Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections
นักวิจัย : Gu, Jun , Fu, Chit Yaw , Ng, Beng Koon , Razul, Sirajudeen Gulam , Lim, Soo Kim
คำค้น : DRNTU::Science::Biological sciences::Microbiology::Immunology
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : Gu, J., Fu, C. Y., Ng, B. K., Razul, S. G., & Lim, S. K. (2014). Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections. Journal of biophotonics, 7(7), 483-491. , 1864-063X , http://hdl.handle.net/10220/24156 , http://dx.doi.org/10.1002/jbio.201200202
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of biophotonics
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The use of conventional fluorescence microscopy for characterizing tissue pathological states is limited by overlapping spectra and the dependence on excitation power and fluorophore concentration. Fluorescence lifetime imaging microscopy (FLIM) can overcome these limitations due to its insensitivity to fluorophore concentration, excitation power and spectral similarity. This study investigates the diagnosis of early cervical cancer using FLIM and a neural network extreme learning machine classifier. A concurrently high sensitivity and specificity of 92.8% and 80.2%, respectively, were achieved. The results suggest that the proposed technique can be used to supplement the traditional histopathological examination of early cervical cancer.

บรรณานุกรม :
Gu, Jun , Fu, Chit Yaw , Ng, Beng Koon , Razul, Sirajudeen Gulam , Lim, Soo Kim . (2557). Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Gu, Jun , Fu, Chit Yaw , Ng, Beng Koon , Razul, Sirajudeen Gulam , Lim, Soo Kim . 2557. "Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Gu, Jun , Fu, Chit Yaw , Ng, Beng Koon , Razul, Sirajudeen Gulam , Lim, Soo Kim . "Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print.
Gu, Jun , Fu, Chit Yaw , Ng, Beng Koon , Razul, Sirajudeen Gulam , Lim, Soo Kim . Quantitative diagnosis of cervical neoplasia using fluorescence lifetime imaging on haematoxylin and eosin stained tissue sections. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.