ridm@nrct.go.th   ระบบคลังข้อมูลงานวิจัยไทย   รายการโปรดที่คุณเลือกไว้

Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells
นักวิจัย : Gong, Tianxun , Olivo, Malini , Dinish, U. S. , Goh, Douglas , Kong, Kien Voon , Yong, Ken-Tye
คำค้น : DRNTU::Science::Medicine::Biomedical engineering
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Gong, T., Olivo, M., Dinish, U. S., Goh, D., Kong, K. V., & Yong, K.-T. (2013). Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells. Journal of biomedical nanotechnology, 9(6), 985-991. , 1550-7033 , http://hdl.handle.net/10220/24122 , http://dx.doi.org/10.1166/jbn.2013.1603
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of biomedical nanotechnology
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

In this paper, we proposed the use of gold nanoparticles as plasmon scattering probes for dark-field multiplex imaging of live cancer cells. By carefully engineering the surfaces, aqueous dispersions of anti-EGFR antibody-conjugated gold nanospheres and gold nanorods are prepared. We demonstrated the receptor-mediated delivery of antibody conjugated gold nanospheres and gold nanorods into EGFR receptor-positive oral squamous cell carcinoma cell line by using dark-field microscopy technique. Our result suggests that gold nanospheres and gold nanorods formulations could provide up to 7 types of plasmon scattering probes based on their tunability range with a 100 nm spectral separation in absorption bands.

บรรณานุกรม :
Gong, Tianxun , Olivo, Malini , Dinish, U. S. , Goh, Douglas , Kong, Kien Voon , Yong, Ken-Tye . (2556). Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Gong, Tianxun , Olivo, Malini , Dinish, U. S. , Goh, Douglas , Kong, Kien Voon , Yong, Ken-Tye . 2556. "Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Gong, Tianxun , Olivo, Malini , Dinish, U. S. , Goh, Douglas , Kong, Kien Voon , Yong, Ken-Tye . "Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print.
Gong, Tianxun , Olivo, Malini , Dinish, U. S. , Goh, Douglas , Kong, Kien Voon , Yong, Ken-Tye . Engineering bioconjugated gold nanospheres and gold nanorods as label-free plasmon scattering probes for ultrasensitive multiplex dark-field imaging of cancer cells. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.