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Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles
นักวิจัย : Peng, Tao , Paramelle, David , Sana, Barindra , Lee, Chiu Fan , Lim, Sierin
คำค้น : DRNTU::Science::Chemistry
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : Peng, T., Paramelle, D., Sana, B., Lee, C. F., & Lim, S. (2014). Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles. Small, 10(15), 3131-3138. , 1613-6810 , http://hdl.handle.net/10220/20893 , http://dx.doi.org/10.1002/smll.201303516
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Small
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

In biomineralization processes, a supramolecular organic structure is often used as a template for inorganic nanomaterial synthesis. The E2 protein cage derived from Geobacillus stearothermophilus pyruvate dehydrogenase and formed by the self-assembly of 60 subunits, has been functionalized with non-native iron-mineralization capability by incorporating two types of iron-binding peptides. The non-native peptides introduced at the interior surface do not affect the self-assembly of E2 protein subunits. In contrast to the wild-type, the engineered E2 protein cages can serve as size- and shape-constrained reactors for the synthesis of iron nanoparticles. Electrostatic interactions between anionic amino acids and cationic iron molecules drive the formation of iron oxide nanoparticles within the engineered E2 protein cages. The work expands the investigations on nanomaterial biosynthesis using engineered host-guest encapsulation properties of protein cages.

บรรณานุกรม :
Peng, Tao , Paramelle, David , Sana, Barindra , Lee, Chiu Fan , Lim, Sierin . (2557). Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Peng, Tao , Paramelle, David , Sana, Barindra , Lee, Chiu Fan , Lim, Sierin . 2557. "Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Peng, Tao , Paramelle, David , Sana, Barindra , Lee, Chiu Fan , Lim, Sierin . "Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2557. Print.
Peng, Tao , Paramelle, David , Sana, Barindra , Lee, Chiu Fan , Lim, Sierin . Designing non-native iron-binding site on a protein cage for biological synthesis of nanoparticles. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2557.