ridm@nrct.go.th   ระบบคลังข้อมูลงานวิจัยไทย   รายการโปรดที่คุณเลือกไว้

Novel tungsten carbide nanorods : an intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Novel tungsten carbide nanorods : an intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents
นักวิจัย : Li, Nan , Yan, Ya , Xia, Bao-Yu , Wang, Jing-Yuan , Wang, Xin
คำค้น : DRNTU::Science::Medicine::Biosensors
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Li, N., Yan, Y., Xia, B.-Y., Wang, J.-Y., & Wang, X. (2014). Novel tungsten carbide nanorods: An intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents. Biosensors and Bioelectronics, 54, 521-527. , 0956-5663 , http://hdl.handle.net/10220/19370 , http://dx.doi.org/10.1016/j.bios.2013.11.040
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Biosensors and bioelectronics
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Tungsten carbide nanorods (WC NRs) are demonstrated for the first time to possess intrinsic peroxidase-like activity towards typical peroxidase substrates, such as 3, 3’, 5, 5’-tetramethylbenzidine (TMB) and o-phenylenediamine (OPD) in the presence of hydrogen peroxide (H2O2). The reactions catalyzed by these nanorods follow the Michaelis-Menten kinetics. The excellent catalytic performance of WC NRs could be attributed to their intrinsic catalytic acitity to efficiently accelerate the electron-transfer process and facilitate the decomposition of H2O2 to generate more numbers of reactive oxygen species (ROS).. Based upon the strong peroxidase-like activity of these WC NRs, a colorimetric sensor for H2O2 is designed, which provides good response towards H2O2 concentration over a range of 2×10-7 to 8×10-5 M with a detection limit of 60 nM. Moreover, the peroxidase-like activities of WC NRs with TMB as the substrate are investigated in both protic and aprotic organic media, showing different colorimetric reactions from that performed in aqueous solutions. In comparison with the natural horse radish peroxidase, WC NR exhibits excellent robustness of catalytic activity and considerable reusability, thus making it a promising mimic of peroxidase catalysts.

บรรณานุกรม :
Li, Nan , Yan, Ya , Xia, Bao-Yu , Wang, Jing-Yuan , Wang, Xin . (2556). Novel tungsten carbide nanorods : an intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Li, Nan , Yan, Ya , Xia, Bao-Yu , Wang, Jing-Yuan , Wang, Xin . 2556. "Novel tungsten carbide nanorods : an intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Li, Nan , Yan, Ya , Xia, Bao-Yu , Wang, Jing-Yuan , Wang, Xin . "Novel tungsten carbide nanorods : an intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print.
Li, Nan , Yan, Ya , Xia, Bao-Yu , Wang, Jing-Yuan , Wang, Xin . Novel tungsten carbide nanorods : an intrinsic peroxidase mimetic with high activity and stability in aqueous and organic solvents. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.