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An improved scoring matrix for multiple sequence alignment

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : An improved scoring matrix for multiple sequence alignment
นักวิจัย : Shu, Jian-Jun , Yong, Kian Yan , Chan, Weng Kong
คำค้น : DRNTU::Engineering::Mathematics and analysis
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Shu, J. J., Yong, K. Y., & Chan, W. K. (2012). An improved scoring matrix for multiple sequence alignment. Mathematical problems in engineering, 2012-490649. , http://hdl.handle.net/10220/18649 , http://dx.doi.org/10.1155/2012/490649 , 162023
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Mathematical problems in engineering
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The way for performing multiple sequence alignment is based on the criterion of the maximum-scored information content computed from a weight matrix, but it is possible to have two or more alignments to have the same highest score leading to ambiguities in selecting the best alignment. This paper addresses this issue by introducing the concept of joint weight matrix to eliminate the randomness in selecting the best multiple sequence alignment. Alignments with equal scores are iteratively rescored with the joint weight matrix of increasing level (nucleotide pairs, triplets, and so on) until one single best alignment is eventually found. This method for resolving ambiguity in multiple sequence alignment can be easily implemented by use of the improved scoring matrix.

บรรณานุกรม :
Shu, Jian-Jun , Yong, Kian Yan , Chan, Weng Kong . (2555). An improved scoring matrix for multiple sequence alignment.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Shu, Jian-Jun , Yong, Kian Yan , Chan, Weng Kong . 2555. "An improved scoring matrix for multiple sequence alignment".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Shu, Jian-Jun , Yong, Kian Yan , Chan, Weng Kong . "An improved scoring matrix for multiple sequence alignment."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Shu, Jian-Jun , Yong, Kian Yan , Chan, Weng Kong . An improved scoring matrix for multiple sequence alignment. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.