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Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging
นักวิจัย : Zhu, Jing , Gong, Tianxun , Kopwitthaya, Atcha , Hu, Rui , Law, Wing-Cheung , Roy, Indrajit , Huang, Huijie , Yong, Ken-Tye
คำค้น : DRNTU::Engineering::Electrical and electronic engineering.
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Zhu, J., Gong, T., Kopwitthaya, A., Hu, R., Law, W.-C., Roy, I., et al. (2013). Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging. RSC Advances, 3(30), 12280-12286. , 2046-2069 , http://hdl.handle.net/10220/17780 , http://dx.doi.org/10.1039/c3ra41777h
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : RSC advances
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

In this contribution, we show that Au NRs functionalized with PEG molecules can be used as absorption nanoprobes for near-infrared imaging in live animals. We have found that the contrast signal of the in vivo image is dependent upon the transmission ability of the NIR light interacting with the different aspect ratios of Au NRs. Our study was focused on absorption in vivo imaging at 700 nm, which is within the transmission window of the skin. NIR absorption in vivo imaging was carried out by subcutaneous injection of mice with PEGylated Au NRs that have a LSPR around 700 nm. The formulation showed strong contrast signals under the tissues upon irradiation with NIR light. More importantly, our theoretical calculation suggested that the high contrast signals from the PEGylated Au NRs were generated via the NIR light absorption of the Au NRs within the tissue.

บรรณานุกรม :
Zhu, Jing , Gong, Tianxun , Kopwitthaya, Atcha , Hu, Rui , Law, Wing-Cheung , Roy, Indrajit , Huang, Huijie , Yong, Ken-Tye . (2556). Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Zhu, Jing , Gong, Tianxun , Kopwitthaya, Atcha , Hu, Rui , Law, Wing-Cheung , Roy, Indrajit , Huang, Huijie , Yong, Ken-Tye . 2556. "Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Zhu, Jing , Gong, Tianxun , Kopwitthaya, Atcha , Hu, Rui , Law, Wing-Cheung , Roy, Indrajit , Huang, Huijie , Yong, Ken-Tye . "Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print.
Zhu, Jing , Gong, Tianxun , Kopwitthaya, Atcha , Hu, Rui , Law, Wing-Cheung , Roy, Indrajit , Huang, Huijie , Yong, Ken-Tye . Synthesis of PEGylated gold nanorods (Au NRs) as absorption nanoprobes for near-infrared optical imaging. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.