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Uniform expansion of a polymeric helical stent

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Uniform expansion of a polymeric helical stent
นักวิจัย : Paryab, Nasim , Cronin, Duane , Lee-Sullivan, Pearl , Ying, Xiong , Boey, Freddy Yin Chiang , Venkatraman, Subbu S.
คำค้น : DRNTU::Engineering::Materials
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Paryab, N., Cronin, D., Lee-Sullivan, P., Ying, X., Boey, F. Y. C., & Venkatraman, S. (2012). Uniform expansion of a polymeric helical stent. Journal of medical devices, 6(2), 021012-. , 1932-6181 , http://hdl.handle.net/10220/17686 , http://dx.doi.org/10.1115/1.4005777
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of medical devices
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Helical coil polymeric stents provide an alternative method of stenting compared to traditional metallic stents, but require additional investigation to understand deployment, expansion, and fixation. A bilayer helical coil stent consisting of PLLA and PLGA was investigated using the finite element model to evaluate performance by uniform expansion and subsequent recoiling. In vitro material characterization studies showed that a preinsertion water-soaking step to mimic body implantation conditions provided the required ductility level expansion. In this case, the mechanical contribution of the outer PLGA layer was negligible since it softened significantly under environmental conditions. The viscoelastic response was not considered in this study since the strain rate during expansion was relatively slow and the material response was primarily plastic. The numerical model was validated with available experimental expansion and recoiling data. A parametric study was then undertaken to investigate the effect of stent geometry and coefficient of friction at the stent-cylinder interface on the expansion and recoiling characteristics. The model showed that helical stents exhibit a uniform stress distribution after expansion, which is important for controlled degradation when using biodegradable materials. The results indicated that increasing stent width, pitch value, and coil thickness resulted in a larger diameter after recoiling, which would improve fixation in the artery. It was also noted that a helical stent should have more than five coils to be stable after recoiling. This work is part of a larger research study focused on the performance of a balloon-inflated polymeric helical stent for artery applications.

บรรณานุกรม :
Paryab, Nasim , Cronin, Duane , Lee-Sullivan, Pearl , Ying, Xiong , Boey, Freddy Yin Chiang , Venkatraman, Subbu S. . (2555). Uniform expansion of a polymeric helical stent.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Paryab, Nasim , Cronin, Duane , Lee-Sullivan, Pearl , Ying, Xiong , Boey, Freddy Yin Chiang , Venkatraman, Subbu S. . 2555. "Uniform expansion of a polymeric helical stent".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Paryab, Nasim , Cronin, Duane , Lee-Sullivan, Pearl , Ying, Xiong , Boey, Freddy Yin Chiang , Venkatraman, Subbu S. . "Uniform expansion of a polymeric helical stent."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Paryab, Nasim , Cronin, Duane , Lee-Sullivan, Pearl , Ying, Xiong , Boey, Freddy Yin Chiang , Venkatraman, Subbu S. . Uniform expansion of a polymeric helical stent. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.