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A rocket-like encapsulation and delivery system with two-stage booster layers : pH-responsive poly(methacrylic acid)/poly(ethylene glycol) complex-coated hollow silica vesicles

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : A rocket-like encapsulation and delivery system with two-stage booster layers : pH-responsive poly(methacrylic acid)/poly(ethylene glycol) complex-coated hollow silica vesicles
นักวิจัย : Lay, Chee Leng , Kumar, Jatin N. , Liu, Connie K. , Lu, Xuehong , Liu, Ye
คำค้น : -
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : Lay, C. L., Kumar, J. N., Liu, C. K., Lu, X., & Liu, Y. (2013). A Rocket-Like Encapsulation and Delivery System with Two-Stage Booster Layers: pH-Responsive Poly(methacrylic acid)/Poly(ethylene glycol) Complex-Coated Hollow Silica Vesicles. Macromolecular Rapid Communications, 34(19), 1563-1568. , http://hdl.handle.net/10220/17945 , http://dx.doi.org/10.1002/marc.201300529
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Macromolecular rapid communications
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Rocket-like vesicles formed are composed of poly(acrylic aicd) (PMAA )/poly(ethylene glycol) (PEG) complex coated hollow silica spheres, and the structure and composition of the vesicles are characterized using TGA, 1H NMR, FTIR, and TEM. Although only one-third of EG units of PEG brushes grafted to hollow silica spheres form the complex with PMAA via hydrogen bonding, the first “booster” layer composed of PMAA/PEG complex can provide secure encapsulation of model compound calcein blue under an acidic condition. The second “booster” layer composed of PEG brushes can be formed by changing acidic pH to 7.4 through the disassociation of the PMAA/PEG complex. A higher molecular weight PMAA exhibits a faster disassembly due to the formation of a looser PMAA/PEG complex on the surfaces of hollow silica spheres.

บรรณานุกรม :
Lay, Chee Leng , Kumar, Jatin N. , Liu, Connie K. , Lu, Xuehong , Liu, Ye . (2556). A rocket-like encapsulation and delivery system with two-stage booster layers : pH-responsive poly(methacrylic acid)/poly(ethylene glycol) complex-coated hollow silica vesicles.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Lay, Chee Leng , Kumar, Jatin N. , Liu, Connie K. , Lu, Xuehong , Liu, Ye . 2556. "A rocket-like encapsulation and delivery system with two-stage booster layers : pH-responsive poly(methacrylic acid)/poly(ethylene glycol) complex-coated hollow silica vesicles".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Lay, Chee Leng , Kumar, Jatin N. , Liu, Connie K. , Lu, Xuehong , Liu, Ye . "A rocket-like encapsulation and delivery system with two-stage booster layers : pH-responsive poly(methacrylic acid)/poly(ethylene glycol) complex-coated hollow silica vesicles."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2556. Print.
Lay, Chee Leng , Kumar, Jatin N. , Liu, Connie K. , Lu, Xuehong , Liu, Ye . A rocket-like encapsulation and delivery system with two-stage booster layers : pH-responsive poly(methacrylic acid)/poly(ethylene glycol) complex-coated hollow silica vesicles. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2556.