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Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide.

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide.
นักวิจัย : Kong, Jen Fong. , Lipik, Vitali T. , Abadie, Marc J. M. , Roshan Deen, G. , Venkatraman, Subbu S.
คำค้น : DRNTU::Engineering::Materials.
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Kong, J. F., Lipik, V., Abadie, M. J. M., Roshan Deen, G., & Venkatraman, S. S. (2012). Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide . Journal of biomedical materials research part A, 100A(12), 3436-3445. , 1552-4965 , http://hdl.handle.net/10220/17668 , http://dx.doi.org/10.1002/jbm.a.34277
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of biomedical materials research part A
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Although biodegradable polymers have found extensive applications in medical areas, there are limited reports that show elastomeric behavior. In this work, a biodegradable, elastomeric polymer is demonstrated from a four-armed star copolymer. With a fixed middle core composition, comprising caprolactone (CL) and L-lactide (LA), an elastomer is obtained by increasing the polylactide (PLA) end block lengths to obtain sufficient end block crystallinity. This increase suppressed the middle core's crystallinity yet ensured cocrystallization of the PLA ends of individual star copolymer chains to form a three-dimensional network via physical crosslinking. Cyclic and creep test of the star copolymers showed that at least 75% of recovery was achieved. Degradation study of the copolymer showed that degradation first occurred in the caprolactone-co-lactide (CLLA) core, followed by degradation in the PLA ends. Chain scission in the middle core resulted in immediate formation of CL crystals within the core and increased crystallinity over time, in both CLLA core and PLA ends.

บรรณานุกรม :
Kong, Jen Fong. , Lipik, Vitali T. , Abadie, Marc J. M. , Roshan Deen, G. , Venkatraman, Subbu S. . (2555). Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide..
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Kong, Jen Fong. , Lipik, Vitali T. , Abadie, Marc J. M. , Roshan Deen, G. , Venkatraman, Subbu S. . 2555. "Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide.".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Kong, Jen Fong. , Lipik, Vitali T. , Abadie, Marc J. M. , Roshan Deen, G. , Venkatraman, Subbu S. . "Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide.."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Kong, Jen Fong. , Lipik, Vitali T. , Abadie, Marc J. M. , Roshan Deen, G. , Venkatraman, Subbu S. . Characterization and degradation of elastomeric four-armed star copolymers based on caprolactone and L-lactide.. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.