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A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry
นักวิจัย : Hoog, Hans-Peter M. de , Nallani, Madhavan , Bo, Liedberg
คำค้น : -
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Hoog, H.-P. M. d., Nallani, M., & Liedberg, B. (2012). A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry. Polymer Chemistry, 3(2), 302-306. , http://hdl.handle.net/10220/16951 , http://dx.doi.org/10.1039/c1py00413a
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Polymer chemistry
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Polymersomes are promising platforms for use in biosensing, where their stability may be crucial over that of liposomes. For the introduction of the desired functionality multiple strategies have been reported for functionalization of polymersomes. However, none of them have combined readily available starting materials, facility and in situ quantification. We show a simple 4-step method for functionalization of polymersomes starting from commercially available materials. For the key conjugation step a recently explored light induced cycloaddition was used which is relatively fast (15 min) and allows in situ quantification by the intrinsic fluorescence of the conjugate. The facility of the protocol, the ease of preparation and quantification make this ‘click’-type conjugation method a promising alternative to the established strained cycloadditions.

บรรณานุกรม :
Hoog, Hans-Peter M. de , Nallani, Madhavan , Bo, Liedberg . (2555). A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Hoog, Hans-Peter M. de , Nallani, Madhavan , Bo, Liedberg . 2555. "A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Hoog, Hans-Peter M. de , Nallani, Madhavan , Bo, Liedberg . "A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Hoog, Hans-Peter M. de , Nallani, Madhavan , Bo, Liedberg . A facile and fast method for the functionalization of polymersomes by photoinduced cycloaddition chemistry. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.