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3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : 3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces
นักวิจัย : Guo, Jinhong , Pui, Tze Sian , Rahman, Abdur Rub Abdur , Kang, Yuejun
คำค้น : -
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Guo, J., Pui, T. S., Rahman, A. R. A.,& Kang, Y. (2013). 3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces. ELECTROPHORESIS, 34(3), 417-424. , 0173-0835 , http://hdl.handle.net/10220/16577 , http://dx.doi.org/10.1002/elps.201200418
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : ELECTROPHORESIS
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Coulter counters have played an important role in biological cell assays since their introduction decades ago. Several types of high throughput micro-Coulter counters based on lab-on-chip devices have been commercialized recently. In this paper, we propose a highly integrated micro-Coulter counter array working under low DC voltage. The real-time electrical current change, including the pulse amplitude and width, of the micro-Coulter counter with novel structure is systematically investigated numerically. The major types of forces exerted on the particle in the micro-Coulter counter, including hydrodynamic force and electrokinetic force are quantitatively analyzed. The simulation in this study shows the pulse profile, such as width and amplitude, is affected by both particle size and the flow condition. The special cases of multiple particle aggregation and cross-talk between neighboring channels are also considered for their effects on the electric current pulses. This simulation provides critical insight and guidance for developing next new generations of micro-Coulter counter.

บรรณานุกรม :
Guo, Jinhong , Pui, Tze Sian , Rahman, Abdur Rub Abdur , Kang, Yuejun . (2555). 3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Guo, Jinhong , Pui, Tze Sian , Rahman, Abdur Rub Abdur , Kang, Yuejun . 2555. "3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Guo, Jinhong , Pui, Tze Sian , Rahman, Abdur Rub Abdur , Kang, Yuejun . "3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Guo, Jinhong , Pui, Tze Sian , Rahman, Abdur Rub Abdur , Kang, Yuejun . 3D numerical simulation of a Coulter counter array with analysis of electrokinetic forces. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.