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Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties
นักวิจัย : Qi, Xiaobao , Gunawan, Poernomo , Xu, Rong , Chang, Matthew Wook
คำค้น : -
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Qi, X., Gunawan, P., Xu, R.,& Chang, M. W. (2012). Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties. Chemical Engineering Science, 84, 552-556. , 0009-2509 , http://hdl.handle.net/10220/12948 , http://dx.doi.org/10.1016/j.ces.2012.08.054
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Chemical engineering science
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Multi-walled carbon nanotubes (MWNTs) possess weak antimicrobial property. In this report, we demonstrate that the covalent immobilization of the antibiotic cefalexin via poly(ethylene glycol) as a linking agent improves the antimicrobial and anti-adhesive properties of MWNTs against both Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus and Bacillus subtilis). In particular, the MWNT-cefalexin composite showed 2-fold higher antimicrobial property than pristine MWNTs against S. aureus and B. subtilis. Moreover, the MWNT-cefalexin deposited film effectively inhibited cell adhesion. Given the simple, inexpensive procedures of our synthesis method, the MWNT-cefalexin composite has the potential to be used as an effective and economical antibacterial and anti-adhesion material for environmental and biomedical applications.

บรรณานุกรม :
Qi, Xiaobao , Gunawan, Poernomo , Xu, Rong , Chang, Matthew Wook . (2555). Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Qi, Xiaobao , Gunawan, Poernomo , Xu, Rong , Chang, Matthew Wook . 2555. "Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Qi, Xiaobao , Gunawan, Poernomo , Xu, Rong , Chang, Matthew Wook . "Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Qi, Xiaobao , Gunawan, Poernomo , Xu, Rong , Chang, Matthew Wook . Cefalexin-immobilized multi-walled carbon nanotubes show strong antimicrobial and anti-adhesion properties. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.