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Investigation of cell morphology by the TRUImagE digital holographic microscopy system

หน่วยงาน Nanyang Technological University, Singapore

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ชื่อเรื่อง : Investigation of cell morphology by the TRUImagE digital holographic microscopy system
นักวิจัย : Chee, Oi Choo , Qu, Weijuan , Chai, Kim Kheong , Asundi, Anand Krishna
คำค้น : DRNTU::Engineering::Mechanical engineering
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Chee, O. C., Qu, W., Chai, K. K., & Asundi, A. K. (2012). Investigation of cell morphology by the TRUImagE digital holographic microscopy system. Proceedings of SPIE - Biophotonics: Photonic Solutions for Better Health Care III, 84272G. , http://hdl.handle.net/10220/12314 , http://dx.doi.org/10.1117/12.921613
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

We report the development of the Three-dimensional Real-time Uninvasive Imaging and Evaluation (TRUImagE) system based on digital holographic microscopy to study the morphological changes in cells undergoing photodynamic therapyinduced cell death. The optical system, based on the Michelson interferometer and configured in transmission mode, and the sample holder incorporating a stage incubator have been developed for monitoring various tumorigenic cell samples without the use of markers. Off-axis digital holograms were recorded with a CCD sensor and numerically reconstructed to provide quantitative phase imaging and 3D morphology of the cells in real time. The system was used to continuously monitor and study, at different time points, the changes in cells after incubation with the photosensitizer followed by activation by the appropriate light dose. Results obtained from the TRUImagE system and biochemical assays will be given.

บรรณานุกรม :
Chee, Oi Choo , Qu, Weijuan , Chai, Kim Kheong , Asundi, Anand Krishna . (2555). Investigation of cell morphology by the TRUImagE digital holographic microscopy system.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Chee, Oi Choo , Qu, Weijuan , Chai, Kim Kheong , Asundi, Anand Krishna . 2555. "Investigation of cell morphology by the TRUImagE digital holographic microscopy system".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Chee, Oi Choo , Qu, Weijuan , Chai, Kim Kheong , Asundi, Anand Krishna . "Investigation of cell morphology by the TRUImagE digital holographic microscopy system."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Chee, Oi Choo , Qu, Weijuan , Chai, Kim Kheong , Asundi, Anand Krishna . Investigation of cell morphology by the TRUImagE digital holographic microscopy system. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.