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Pluronic triblock copolymer encapsulated gold nanorods as biocompatible localized plasmon resonance-enhanced scattering probes for dark-field imaging of cancer cells

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Pluronic triblock copolymer encapsulated gold nanorods as biocompatible localized plasmon resonance-enhanced scattering probes for dark-field imaging of cancer cells
นักวิจัย : Goh, Douglas , Gong, Tianxun , Dinish, U. S. , Maiti, Kaustabh Kumar , Fu, Chit Yaw , Yong, Ken-Tye , Olivo, Malini
คำค้น : -
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : Goh, D., Gong, T., Dinish, U. S., Maiti, K. K., Fu, C. Y., Yong, K.-T., et al. (2012). Pluronic Triblock Copolymer Encapsulated Gold Nanorods as Biocompatible Localized Plasmon Resonance-Enhanced Scattering Probes for Dark-Field Imaging of Cancer Cells. Plasmonics, 7(4), 595-601. , 1557-1955 , http://hdl.handle.net/10220/10576 , http://dx.doi.org/10.1007/s11468-012-9347-3
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Plasmonics
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Gold nanorods (GNR) are synthesized using cetylmethylammonium bromide (CTAB) surfactants which function as structure-directing agents. However, CTAB forms a tightly bound cationic bilayer on GNR surface with the cationic trimethylammonium head group exposed to the aqueous media, which is known to be highly toxic in vitro and in vivo. Pluronic is a non-ionic triblock polymer, which can associate with CTAB and form stable CTAB–polymer complexes due to hydrophobic interactions. In this work, two types of Pluronic triblock copolymers were used to encapsulate GNR to reduce their cytotoxicity and improve colloidal and optical stability for biological applications. These formulations were characterized by UV–vis absorption spectra analysis, transmission electron microscopy, cell viability studies, differential interference contrast microscopy and dark-field imaging.

บรรณานุกรม :
Goh, Douglas , Gong, Tianxun , Dinish, U. S. , Maiti, Kaustabh Kumar , Fu, Chit Yaw , Yong, Ken-Tye , Olivo, Malini . (2555). Pluronic triblock copolymer encapsulated gold nanorods as biocompatible localized plasmon resonance-enhanced scattering probes for dark-field imaging of cancer cells.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Goh, Douglas , Gong, Tianxun , Dinish, U. S. , Maiti, Kaustabh Kumar , Fu, Chit Yaw , Yong, Ken-Tye , Olivo, Malini . 2555. "Pluronic triblock copolymer encapsulated gold nanorods as biocompatible localized plasmon resonance-enhanced scattering probes for dark-field imaging of cancer cells".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Goh, Douglas , Gong, Tianxun , Dinish, U. S. , Maiti, Kaustabh Kumar , Fu, Chit Yaw , Yong, Ken-Tye , Olivo, Malini . "Pluronic triblock copolymer encapsulated gold nanorods as biocompatible localized plasmon resonance-enhanced scattering probes for dark-field imaging of cancer cells."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2555. Print.
Goh, Douglas , Gong, Tianxun , Dinish, U. S. , Maiti, Kaustabh Kumar , Fu, Chit Yaw , Yong, Ken-Tye , Olivo, Malini . Pluronic triblock copolymer encapsulated gold nanorods as biocompatible localized plasmon resonance-enhanced scattering probes for dark-field imaging of cancer cells. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2555.