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Graphene-based biosensors for detection of bacteria and their metabolic activities

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Graphene-based biosensors for detection of bacteria and their metabolic activities
นักวิจัย : Huang, Yinxi , Dong, Xiaochen , Liu, Yuxin , Li, Lain-Jong , Chen, Peng
คำค้น : DRNTU::Science::Chemistry::Organic chemistry::Antibiotics
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2554
อ้างอิง : Huang, Y., Dong, X., Liu, Y., Li, L. J., & Chen, P. (2011). Graphene-based biosensors for detection of bacteria and their metabolic activities. Journal of Materials Chemistry, 21, 12358–12362. , http://hdl.handle.net/10220/7545 , http://dx.doi.org/10.1039/c1jm11436k , 163170
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Journal of materials chemistry
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Graphene, which is a recently discovered single-atom-thick planar sheet of carbon atoms perfectly arranged in a honeycomb lattice, has great potential in biosensing owing to its extraordinary electrical, physical, and optical properties. In this work, we demonstrate a graphene based biosensor to electrically detect E. coli bacteria with high sensitivity and specificity. The large-sized graphene film was grown by chemical vapor deposition and functionalized with anti-E. coli antibodies and passivation layer. Significant conductance increase of the graphene device was observed after exposure to E. coli bacteria at a concentration as low as 10 cfu/mL, while no significant response was triggered by high concentration of the another bacterial strain. In addition, this biosensor was employed to detect the glucose induced metabolic activities of the bound E. coli bacteria in real time. This simple, fast, sensitive, and label-free nanoelectronic biosensor, in principle, could serve as a high throughput platform for detection of any pathogenic bacteria, and for functional studies or screening of antibacterial drugs.

บรรณานุกรม :
Huang, Yinxi , Dong, Xiaochen , Liu, Yuxin , Li, Lain-Jong , Chen, Peng . (2554). Graphene-based biosensors for detection of bacteria and their metabolic activities.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Huang, Yinxi , Dong, Xiaochen , Liu, Yuxin , Li, Lain-Jong , Chen, Peng . 2554. "Graphene-based biosensors for detection of bacteria and their metabolic activities".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Huang, Yinxi , Dong, Xiaochen , Liu, Yuxin , Li, Lain-Jong , Chen, Peng . "Graphene-based biosensors for detection of bacteria and their metabolic activities."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2554. Print.
Huang, Yinxi , Dong, Xiaochen , Liu, Yuxin , Li, Lain-Jong , Chen, Peng . Graphene-based biosensors for detection of bacteria and their metabolic activities. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2554.