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Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors
นักวิจัย : Gui, Ee Ling , Li, Lain-Jong , Lee, Pooi See , Lohani, Anup , Mhaisalkar, Subodh Gautam , Cao, Qing , Kang, Seong Jun , Rogers, John A. , Tansil, Natalia Chendrawati , Gao, Zhiqiang
คำค้น : DRNTU::Engineering::Materials::Nanostructured materials.
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2549
อ้างอิง : Gui, E. L., Li, L. J., Lee, P. S., Lohani, A., Mhaisalkar, S. G., Cao, Q., et al. (2006). Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field effect transistors. Applied physics letters, 89(23). , http://hdl.handle.net/10220/8095 , http://dx.doi.org/10.1063/1.2399355
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Applied physics letters
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The authors study deoxyribonucleic acid (DNA) sensing characteristics of carbon nanotube network field-effect transistors (CNNFETs) by monitoring their electrical responses upon immobilization with a DNA probe, hybridization with DNA analytes, and intercalation with a N,N'-bis(3-propylimidazole)-1,4,5,8-naphthalene diimide modified with Os(2,2'-bipyridine)2Cl+ pendants. The CNNFETs immobilized by single-stranded DNA molecules demonstrate the selective sensing of its complementary and single-base mismatched DNA (difference of ~16% in reduction of normalized drain current Id). Subsequent intercalation demonstrates a further sensitivity enhancement (difference of ~13% in Id reduction due to specific binding between hybridized DNA and intercalators, corroborated by the x-ray photoelectron spectroscopy study.

บรรณานุกรม :
Gui, Ee Ling , Li, Lain-Jong , Lee, Pooi See , Lohani, Anup , Mhaisalkar, Subodh Gautam , Cao, Qing , Kang, Seong Jun , Rogers, John A. , Tansil, Natalia Chendrawati , Gao, Zhiqiang . (2549). Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Gui, Ee Ling , Li, Lain-Jong , Lee, Pooi See , Lohani, Anup , Mhaisalkar, Subodh Gautam , Cao, Qing , Kang, Seong Jun , Rogers, John A. , Tansil, Natalia Chendrawati , Gao, Zhiqiang . 2549. "Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
Gui, Ee Ling , Li, Lain-Jong , Lee, Pooi See , Lohani, Anup , Mhaisalkar, Subodh Gautam , Cao, Qing , Kang, Seong Jun , Rogers, John A. , Tansil, Natalia Chendrawati , Gao, Zhiqiang . "Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2549. Print.
Gui, Ee Ling , Li, Lain-Jong , Lee, Pooi See , Lohani, Anup , Mhaisalkar, Subodh Gautam , Cao, Qing , Kang, Seong Jun , Rogers, John A. , Tansil, Natalia Chendrawati , Gao, Zhiqiang . Electrical detection of hybridization and threading intercalation of deoxyribonucleic acid using carbon nanotube network field-effect transistors. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2549.