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Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method

หน่วยงาน Nanyang Technological University, Singapore

รายละเอียด

ชื่อเรื่อง : Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method
นักวิจัย : You, Chang Cheng , Zhao, Yanli , Liu, Yu
คำค้น : DRNTU::Science::Biological sciences::Biochemistry.
หน่วยงาน : Nanyang Technological University, Singapore
ผู้ร่วมงาน : -
ปีพิมพ์ : 2544
อ้างอิง : You, C. C., Zhao, Y. L., & Liu, Y. (2001). Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method. Chemical journal of Chinese universities, 22(2), 218-222. , 0251-0790 , http://hdl.handle.net/10220/6993 , 159616
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : Chemical journal of Chinese universities
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Spectrophotometric titrations were performed in aqueous buffer solution ( pH = 10. 5 , c =0. 025 mol/ L) at 25ᵒC determine the binding constant s of β-cyclodextrin (β-CD) , mono (6-O-α-malto-syl)- β-cyclodextrin (6-G2-β-CD) and mono [2-O-(2-hydroxypropyl)]-β-cyclodextrin (2-HP-β-CD) with several aliphatic chiral guest molecules using phenolphthalein as a spectral probe. The results obtained indicate that several weak interactions cooperatively contribute to the inclusion complexation of the β-cyclodextrin hosts and the complex stability is dominated by the size/shape-matching between host and guest. The substituent on the cyclodextrin derivatives changes it s original binding ability. For the relatively small guest molecules, i. e. , borneol , camphor and menthol , the molecular binding ability is 2-HP-β-CD > β-CD >6-G2-β-CD. Furthermore, the three β-cyclodextrin host s can also serve as chiral discrimination reagents and afford stronger binding ability toward ( + )-isomers. Among them, 2-HP-β-CD gives a moderate enantiometric selectivity of 1. 25 for ( + ) / ( - )-camphor.

บรรณานุกรม :
You, Chang Cheng , Zhao, Yanli , Liu, Yu . (2544). Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method.
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
You, Chang Cheng , Zhao, Yanli , Liu, Yu . 2544. "Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method".
    กรุงเทพมหานคร : Nanyang Technological University, Singapore.
You, Chang Cheng , Zhao, Yanli , Liu, Yu . "Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method."
    กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2544. Print.
You, Chang Cheng , Zhao, Yanli , Liu, Yu . Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2544.