ชื่อเรื่อง | : | Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method |
นักวิจัย | : | You, Chang Cheng , Zhao, Yanli , Liu, Yu |
คำค้น | : | DRNTU::Science::Biological sciences::Biochemistry. |
หน่วยงาน | : | Nanyang Technological University, Singapore |
ผู้ร่วมงาน | : | - |
ปีพิมพ์ | : | 2544 |
อ้างอิง | : | You, C. C., Zhao, Y. L., & Liu, Y. (2001). Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method. Chemical journal of Chinese universities, 22(2), 218-222. , 0251-0790 , http://hdl.handle.net/10220/6993 , 159616 |
ที่มา | : | - |
ความเชี่ยวชาญ | : | - |
ความสัมพันธ์ | : | Chemical journal of Chinese universities |
ขอบเขตของเนื้อหา | : | - |
บทคัดย่อ/คำอธิบาย | : | Spectrophotometric titrations were performed in aqueous buffer solution ( pH = 10. 5 , c =0. 025 mol/ L) at 25ᵒC determine the binding constant s of β-cyclodextrin (β-CD) , mono (6-O-α-malto-syl)- β-cyclodextrin (6-G2-β-CD) and mono [2-O-(2-hydroxypropyl)]-β-cyclodextrin (2-HP-β-CD) with several aliphatic chiral guest molecules using phenolphthalein as a spectral probe. The results obtained indicate that several weak interactions cooperatively contribute to the inclusion complexation of the β-cyclodextrin hosts and the complex stability is dominated by the size/shape-matching between host and guest. The substituent on the cyclodextrin derivatives changes it s original binding ability. For the relatively small guest molecules, i. e. , borneol , camphor and menthol , the molecular binding ability is 2-HP-β-CD > β-CD >6-G2-β-CD. Furthermore, the three β-cyclodextrin host s can also serve as chiral discrimination reagents and afford stronger binding ability toward ( + )-isomers. Among them, 2-HP-β-CD gives a moderate enantiometric selectivity of 1. 25 for ( + ) / ( - )-camphor. |
บรรณานุกรม | : |
You, Chang Cheng , Zhao, Yanli , Liu, Yu . (2544). Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method.
กรุงเทพมหานคร : Nanyang Technological University, Singapore. You, Chang Cheng , Zhao, Yanli , Liu, Yu . 2544. "Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method".
กรุงเทพมหานคร : Nanyang Technological University, Singapore. You, Chang Cheng , Zhao, Yanli , Liu, Yu . "Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method."
กรุงเทพมหานคร : Nanyang Technological University, Singapore, 2544. Print. You, Chang Cheng , Zhao, Yanli , Liu, Yu . Molecular recognition study of β-cyclodextrin and its two derivatives with some aliphatic guests by competitive inclusion method. กรุงเทพมหานคร : Nanyang Technological University, Singapore; 2544.
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