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Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves

หน่วยงาน Universiti Sains Malaysia, Malaysia

รายละเอียด

ชื่อเรื่อง : Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves
นักวิจัย : Ismail, Tuan Nadrah Naim Tuan , Salleh, Siti Farhanah Mohd , Ismail, Norzila , Ibrahim, Wan Suriyani Wan
คำค้น : RC254-282 Neoplasms. Tumors. Oncology (including Cancer)
หน่วยงาน : Universiti Sains Malaysia, Malaysia
ผู้ร่วมงาน : -
ปีพิมพ์ : 2563
อ้างอิง : http://eprints.usm.my/44086/1/Phytochemical%20Screening%20and%20Cytotoxic%20Effects%20of%20Crude%20Extracts%20of%20Pereskia%20Bleo%20Leaves%20%281%29.pdf , Salleh, Siti Farhanah Mohd and Ismail, Norzila and Ibrahim, Wan Suriyani Wan and Ismail, Tuan Nadrah Naim Tuan (2020) Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves. Journal of Herbs, Spices and Medicinal Plants. ISSN 1540-3580 (Submitted)
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : http://eprints.usm.my/44086/ , https://www.tandfonline.com/doi/full/10.1080/10496475.2020.1729287
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

The phytocompounds in crude solvent extracts of Pereskia bleo leaves were identified and their cytotoxic effects on cancer cell lines were determined. Crude extracts were obtained via maceration and subjected to GCMS analysis. Then, each extract was incubated with HeLa, MDA-MB-231, SW480, and NIH/3T3 cell lines for 72 h. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay was done to determine IC50 values of each extract. Terpenoids, sterols, alkaloids, fatty acids and phenolic compounds were identified from the crude extracts of P. bleo leaves. Other compounds identified were γ-sitosterol, β-tocopherol, and γ-tocopherol. The ethyl acetate extract had potent cytotoxic effect against HeLa and MDA-MB-231 cancer cells as noted by the lowest IC50 values

บรรณานุกรม :
Ismail, Tuan Nadrah Naim Tuan , Salleh, Siti Farhanah Mohd , Ismail, Norzila , Ibrahim, Wan Suriyani Wan . (2563). Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves.
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia.
Ismail, Tuan Nadrah Naim Tuan , Salleh, Siti Farhanah Mohd , Ismail, Norzila , Ibrahim, Wan Suriyani Wan . 2563. "Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves".
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia.
Ismail, Tuan Nadrah Naim Tuan , Salleh, Siti Farhanah Mohd , Ismail, Norzila , Ibrahim, Wan Suriyani Wan . "Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves."
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia, 2563. Print.
Ismail, Tuan Nadrah Naim Tuan , Salleh, Siti Farhanah Mohd , Ismail, Norzila , Ibrahim, Wan Suriyani Wan . Phytochemical Screening and Cytotoxic Effects of Crude Extracts of Pereskia Bleo Leaves. กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia; 2563.