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Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives

หน่วยงาน Universiti Sains Malaysia, Malaysia

รายละเอียด

ชื่อเรื่อง : Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives
นักวิจัย : Periayah, Mercy Halleluyah , Halim , Ahmad Sukari , Yaacob, Nik Soriani , Mat Saad, Arman Zaharil , Hussein, Abdul Rahim , Abdul Rashid, Ahmad Hazri
คำค้น : RA0421 Public health. Hygiene. Preventive Medicine , TP Chemical Technology
หน่วยงาน : Universiti Sains Malaysia, Malaysia
ผู้ร่วมงาน : -
ปีพิมพ์ : 2557
อ้างอิง : http://eprints.usm.my/37226/1/article3.pdf , Periayah, Mercy Halleluyah and Halim , Ahmad Sukari and Yaacob, Nik Soriani and Mat Saad, Arman Zaharil and Hussein, Abdul Rahim and Abdul Rashid, Ahmad Hazri (2014) Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives. Online International Interdisciplinary Research Journal, IV. pp. 5-14. ISSN 2249-9598
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : http://www.oiirj.org/oiirj/March2014-special-issue/02.pdf , http://eprints.usm.my/37226/
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Chitosan is a natural macromolecular polysaccharide, derived from chitin extracted from the exoskeleton of some marine invertebrates. This study was designed to evaluate the expression of P-selectin, thromboxane A2 (TXA2), transforming growth factor-β1 (TGF- β1) and platelet derived growth factor-AB (PDGF-AB) using enzyme-linked immunosorbent assays (ELISAs). The chitosan derivatives utilized were 7% N,Ocarboxymethylchitosan (NO-CMC) (with 0.45 mL collagen), 8% NO-CMC, oligo - chitosan (O-C) and oligo -chitosan 53 (O-C 53). We found that O-C showed a significantly superior effect compared to NO-CMC in achieving hemostasis. Post-hoc multiple comparisons using Scheffe test indicated that p-values between the mean differences of all the assayed chitosan derivatives were not significant. However, our analyses successfully identified distinctions between the O-C and NO-CMC test groups and blood alone. These results may expand the understanding of the ability of chitosan derivatives to promote inflammatory responses and angiogenesis depending on their physical and chemical structures

บรรณานุกรม :
Periayah, Mercy Halleluyah , Halim , Ahmad Sukari , Yaacob, Nik Soriani , Mat Saad, Arman Zaharil , Hussein, Abdul Rahim , Abdul Rashid, Ahmad Hazri . (2557). Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives.
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia.
Periayah, Mercy Halleluyah , Halim , Ahmad Sukari , Yaacob, Nik Soriani , Mat Saad, Arman Zaharil , Hussein, Abdul Rahim , Abdul Rashid, Ahmad Hazri . 2557. "Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives".
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia.
Periayah, Mercy Halleluyah , Halim , Ahmad Sukari , Yaacob, Nik Soriani , Mat Saad, Arman Zaharil , Hussein, Abdul Rahim , Abdul Rashid, Ahmad Hazri . "Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives."
    กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia, 2557. Print.
Periayah, Mercy Halleluyah , Halim , Ahmad Sukari , Yaacob, Nik Soriani , Mat Saad, Arman Zaharil , Hussein, Abdul Rahim , Abdul Rashid, Ahmad Hazri . Expression of P-selectin, TXA2, TGF-β1 and PDGF-AB in the Presence of Bioadhesive Chitosan Derivatives. กรุงเทพมหานคร : Universiti Sains Malaysia, Malaysia; 2557.