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Human Papillomavirus infection and cervical lesions in HIV infected women on antiretroviral treatment in Thailand

หน่วยงาน มหาวิทยาลัยเชียงใหม่

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ชื่อเรื่อง : Human Papillomavirus infection and cervical lesions in HIV infected women on antiretroviral treatment in Thailand
นักวิจัย : Delory T. , Ngo-Giang-Huong N. , Rangdaeng S. , Chotivanich N. , Limtrakul A. , Putiyanun C. , Suriyachai P. , Matanasarawut W. , Jarupanich T. , Liampongsabuddhi P. , Heard I. , Jourdain G. , Lallemant M. , Le Coeur S. , Zarca K. , Brunet-Possenti F. , Blake A. , Althaus T. , Gallot C. , Desbiolles A. , Fayard F. , Dib F. , Le Pluart D. , Proute M. , Tiv M. , Banchongkit S. , Bowonwatanuwong C. , Buranabanjasatean S. , Chutanunta A. , Eiamsirikit N.
คำค้น : -
หน่วยงาน : มหาวิทยาลัยเชียงใหม่
ผู้ร่วมงาน : -
ปีพิมพ์ : 2560
อ้างอิง : 01634453 , 2-s2.0-85015384329 , 10.1016/j.jinf.2017.02.007 , https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85015384329&origin=inward , http://cmuir.cmu.ac.th/jspui/handle/6653943832/40525
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

© 2017 The British Infection Association Objectives To estimate the prevalence and factors associated with Human Papillomavirus (HPV) infection, HPV genotypes and cytological/histological high-grade (HSIL+/CIN2+) lesions. Methods We conducted a cross-sectional study within a prospective cohort of HIV-infected women on combination antiretroviral therapy (cART). Cervical specimens were collected for cytology and HPV genotyping (Papillocheck ® ). Any women with High-Risk-HPV (HR-HPV), and/or potentially HR-HPV (pHR-HPV) and/or ASC-US or higher (ASC-US+) lesions were referred for colposcopy. Factors associated with HR-HPV infection and with HSIL+/CIN2+ lesions were investigated using mixed-effects logistic regression models. Results 829 women were enrolled: median age 40.4 years, on cART for a median of 6.9 years, median CD4 cell-count 536 cells/mm3, and 788 (96%) with HIV-viral load < 50copies/mL. Of 214 (26%) infected with HPV: 159 (19%) had ≥1 HR-HPV, of whom 38 (5%) HPV52, 22 (3%) HPV16, 9 (1%) HPV18; 21 (3%) had pHR-HPV, 34 (4%) low risk-HPV infection, and 56 (26%) had multiple genotypes. Younger age, low CD4 cell-counts and low education were independently associated with HR-HPV infection. 72 women (9%) had ASC-US+ and 28 (3%) HSIL+/CIN2+ lesions. HR-HPV infection was independently associated with HSIL+/CIN2+ lesions. Conclusion The prevalence of HPV infection and of cervical lesions was low. The HPV genotype distribution supports the use of 9-valent vaccine in Thailand.

บรรณานุกรม :
Delory T. , Ngo-Giang-Huong N. , Rangdaeng S. , Chotivanich N. , Limtrakul A. , Putiyanun C. , Suriyachai P. , Matanasarawut W. , Jarupanich T. , Liampongsabuddhi P. , Heard I. , Jourdain G. , Lallemant M. , Le Coeur S. , Zarca K. , Brunet-Possenti F. , Blake A. , Althaus T. , Gallot C. , Desbiolles A. , Fayard F. , Dib F. , Le Pluart D. , Proute M. , Tiv M. , Banchongkit S. , Bowonwatanuwong C. , Buranabanjasatean S. , Chutanunta A. , Eiamsirikit N. . (2560). Human Papillomavirus infection and cervical lesions in HIV infected women on antiretroviral treatment in Thailand.
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Delory T. , Ngo-Giang-Huong N. , Rangdaeng S. , Chotivanich N. , Limtrakul A. , Putiyanun C. , Suriyachai P. , Matanasarawut W. , Jarupanich T. , Liampongsabuddhi P. , Heard I. , Jourdain G. , Lallemant M. , Le Coeur S. , Zarca K. , Brunet-Possenti F. , Blake A. , Althaus T. , Gallot C. , Desbiolles A. , Fayard F. , Dib F. , Le Pluart D. , Proute M. , Tiv M. , Banchongkit S. , Bowonwatanuwong C. , Buranabanjasatean S. , Chutanunta A. , Eiamsirikit N. . 2560. "Human Papillomavirus infection and cervical lesions in HIV infected women on antiretroviral treatment in Thailand".
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Delory T. , Ngo-Giang-Huong N. , Rangdaeng S. , Chotivanich N. , Limtrakul A. , Putiyanun C. , Suriyachai P. , Matanasarawut W. , Jarupanich T. , Liampongsabuddhi P. , Heard I. , Jourdain G. , Lallemant M. , Le Coeur S. , Zarca K. , Brunet-Possenti F. , Blake A. , Althaus T. , Gallot C. , Desbiolles A. , Fayard F. , Dib F. , Le Pluart D. , Proute M. , Tiv M. , Banchongkit S. , Bowonwatanuwong C. , Buranabanjasatean S. , Chutanunta A. , Eiamsirikit N. . "Human Papillomavirus infection and cervical lesions in HIV infected women on antiretroviral treatment in Thailand."
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2560. Print.
Delory T. , Ngo-Giang-Huong N. , Rangdaeng S. , Chotivanich N. , Limtrakul A. , Putiyanun C. , Suriyachai P. , Matanasarawut W. , Jarupanich T. , Liampongsabuddhi P. , Heard I. , Jourdain G. , Lallemant M. , Le Coeur S. , Zarca K. , Brunet-Possenti F. , Blake A. , Althaus T. , Gallot C. , Desbiolles A. , Fayard F. , Dib F. , Le Pluart D. , Proute M. , Tiv M. , Banchongkit S. , Bowonwatanuwong C. , Buranabanjasatean S. , Chutanunta A. , Eiamsirikit N. . Human Papillomavirus infection and cervical lesions in HIV infected women on antiretroviral treatment in Thailand. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2560.