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Gender difference in accumulation of calcium and phosphorus in the left coronary arteries of Thais

หน่วยงาน มหาวิทยาลัยเชียงใหม่

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ชื่อเรื่อง : Gender difference in accumulation of calcium and phosphorus in the left coronary arteries of Thais
นักวิจัย : Tohno,Y. , Tohno,S. , Mahakkanukrauh,P. , Minami,T. , Sinthubua,A. , Suwannahoy,P. , Ongkana,N. , Laowatthanaphong,S. , Azuma,C.
คำค้น : Clinical Biochemistry , Endocrinology, Diabetes and Metabolism , Biochemistry (medical) , Biochemistry , Inorganic Chemistry
หน่วยงาน : มหาวิทยาลัยเชียงใหม่
ผู้ร่วมงาน : -
ปีพิมพ์ : 2554
อ้างอิง : 01634984 , 2-s2.0-84155172558 , 10.1007/s12011-011-9016-y , 21547401 , http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84155172558&origin=inward , http://cmuir.cmu.ac.th/handle/6653943832/38183
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

To examine whether there were gender differences in compositional changes of the coronary artery with aging, the authors investigated the gender difference in age-related changes of elements in the left coronary arteries of Thais by direct chemical analysis. After ordinary dissections by students at Chiang Mai University were finished, the left coronary arteries were resected from Thai subjects. The Thai subjects consisted of 69 men and 34 women. The ages of the male subjects ranged from 25 to 87 years (average age=62.6±11.4 years) and of the female subjects from 24 to 86 years (average age=59.4±14.6 years). After incinerating the arteries with nitric acid and perchloric acid, the element content was determined by inductively coupled plasma-atomic emission spectrometry. The Ca and P contents tended to increase in the left coronary arteries of men with age, but the increases were not statistically significant. In the left coronary arteries of women, the Ca and P contents increased significantly and progressively with aging. In addition, the Na content increased significantly in the left coronary arteries of both men and women with aging. The differences in the average contents of Ca and P by age group were observed between the left coronary arteries of men and women. With Student's t test, significant gender differences in the average contents of Ca and P were found in both the 40s and the 70s. The Ca and P contents of the left coronary arteries in the 40s were significantly higher in men than in women. In contrast, the Ca and P contents in the 70s were significantly higher in women than in men. These results indicated that the accumulation of Ca and P in the left coronary arteries of Thais occurred at least 10 years earlier in men than in women, but a higher accumulation of Ca and P in old age occurred in the left coronary arteries of women compared with those of men. The present study revealed that there were significant gender differences inthe left coronary arteries with regard to the accumulation of Ca and P with aging. It is reasonable to presume that taking clinical findings into consideration, the gender differences in the left coronary arteries may result from hormonal and/or genetic factors rather than lifestyle factors. © Springer Science+Business Media, LLC 2011.

บรรณานุกรม :
Tohno,Y. , Tohno,S. , Mahakkanukrauh,P. , Minami,T. , Sinthubua,A. , Suwannahoy,P. , Ongkana,N. , Laowatthanaphong,S. , Azuma,C. . (2554). Gender difference in accumulation of calcium and phosphorus in the left coronary arteries of Thais.
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Tohno,Y. , Tohno,S. , Mahakkanukrauh,P. , Minami,T. , Sinthubua,A. , Suwannahoy,P. , Ongkana,N. , Laowatthanaphong,S. , Azuma,C. . 2554. "Gender difference in accumulation of calcium and phosphorus in the left coronary arteries of Thais".
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Tohno,Y. , Tohno,S. , Mahakkanukrauh,P. , Minami,T. , Sinthubua,A. , Suwannahoy,P. , Ongkana,N. , Laowatthanaphong,S. , Azuma,C. . "Gender difference in accumulation of calcium and phosphorus in the left coronary arteries of Thais."
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2554. Print.
Tohno,Y. , Tohno,S. , Mahakkanukrauh,P. , Minami,T. , Sinthubua,A. , Suwannahoy,P. , Ongkana,N. , Laowatthanaphong,S. , Azuma,C. . Gender difference in accumulation of calcium and phosphorus in the left coronary arteries of Thais. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2554.