ชื่อเรื่อง | : | Caffeic acid and its derivatives as heme oxygenase 1 inducer in Hep G2 cell line |
นักวิจัย | : | Jaikang C. , Chaiyasut C. |
คำค้น | : | - |
หน่วยงาน | : | มหาวิทยาลัยเชียงใหม่ |
ผู้ร่วมงาน | : | - |
ปีพิมพ์ | : | 2553 |
อ้างอิง | : | 19960875 , http://www.scopus.com/inward/record.url?eid=2-s2.0-77954070002&partnerID=40&md5=b554f938e1925f833be17d7c9bda9527 , http://cmuir.cmu.ac.th/handle/6653943832/4610 |
ที่มา | : | - |
ความเชี่ยวชาญ | : | - |
ความสัมพันธ์ | : | - |
ขอบเขตของเนื้อหา | : | - |
บทคัดย่อ/คำอธิบาย | : | Effect of 10, 50 and 100 μg/ml caffeic acid and its esters and amides derivatives on heme oxygenase 1 (HO-1) activity induction in Hep G2 cell line was studied. It was found that caffeic acid ester derivatives could induce HO-1 activity more than amide derivatives. The longer side chain and aromatic side chain affected HO-1 activity. At 10 μg/ml concentration, phenylmethyl 1-(3', 4'-dihydroxyphenyl) propenate (PMDP) had 2.1-fold more activity when compared with control. At 50 and 100 μg/ml concentrations, phenylethyl 1-(3', 4'-dihydroxyphenyl) propenate (PEDP) was the highest HO-1 inducer, whose activity was 2.1- and 2.3-fold greater, respectively, when compared with the control group. Caffeic acid and all derivatives induced HO-1 activity on a higher level than curcumin, positive control. This study implied that caffeic acid and its derivatives could be used to induce HO-1 to protect tissues against free radicals. © 2010 Academic Journals. |
บรรณานุกรม | : |
Jaikang C. , Chaiyasut C. . (2553). Caffeic acid and its derivatives as heme oxygenase 1 inducer in Hep G2 cell line.
เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ . Jaikang C. , Chaiyasut C. . 2553. "Caffeic acid and its derivatives as heme oxygenase 1 inducer in Hep G2 cell line".
เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ . Jaikang C. , Chaiyasut C. . "Caffeic acid and its derivatives as heme oxygenase 1 inducer in Hep G2 cell line."
เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2553. Print. Jaikang C. , Chaiyasut C. . Caffeic acid and its derivatives as heme oxygenase 1 inducer in Hep G2 cell line. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2553.
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