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Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country

หน่วยงาน มหาวิทยาลัยเชียงใหม่

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ชื่อเรื่อง : Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country
นักวิจัย : Suriya C. , Kasatpibal N. , Kunaviktikul W. , Kayee T.
คำค้น : -
หน่วยงาน : มหาวิทยาลัยเชียงใหม่
ผู้ร่วมงาน : -
ปีพิมพ์ : 2555
อ้างอิง : 11787023 , 10.2147/CEG.S35211 , http://www.scopus.com/inward/record.url?eid=2-s2.0-84867120245&partnerID=40&md5=f507873d9c5b1349d8a99dcc2217792c , http://cmuir.cmu.ac.th/handle/6653943832/4405
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Objective: To perform and confirm a simplified diagnostic indicators scoring system for predicting peptic ulcer perforation (PUP). Methods: A case-control study was conducted including 812 consecutive patients with PUP from retrospective medical records. Each diagnostic indicator measurable at the time of admittance was analyzed by a multiple regression. Stepwise logistic regression was applied with backward elimination of statistically significant predictors from the full model, with P ≥ 0.05 for exclusion. The item scores were transformed from regression coefficients and computed to a total score. The risk of PUP was interpreted using total scores as a simple predictor. This system was internally validated in 218 consecutive patients and compared to existing systems. Results: A PUP risk score was determined from the diagnostic indicators associated with PUP: gender, age, nonsteroidal antiinflammatory drugs used, history of peptic ulcer, intense abdominal pain, guarding, X-ray free air positive, and referral from other hospitals. Item scores ranged from 0-6.0 and the total score ranged from 0-34.0. The area under the receiver operating characteristic curve shows that there was 91.73% accuracy in the total scores predicting the likelihood of PUP. The likelihood of PUP among low risk (scores < 10.5), moderate risk (scores 11-21), and high risk (scores ≥ 21.5) patients was 0.13, 11.44, and 1.95, respectively. Conclusion: This scoring system is an effective diagnostic indicator for identifying the complex cases of PUP. It is a simple system and can help guide clinicians, providing them with a more efficient way to accurately subgroup patients while also reducing potential biases. © 2012 Suriya et al, publisher and licensee Dove Medical Press Ltd.

บรรณานุกรม :
Suriya C. , Kasatpibal N. , Kunaviktikul W. , Kayee T. . (2555). Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country.
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Suriya C. , Kasatpibal N. , Kunaviktikul W. , Kayee T. . 2555. "Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country".
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Suriya C. , Kasatpibal N. , Kunaviktikul W. , Kayee T. . "Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country."
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2555. Print.
Suriya C. , Kasatpibal N. , Kunaviktikul W. , Kayee T. . Development of a simplified diagnostic indicators scoring system and validation for peptic ulcer perforation in a developing country. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2555.