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Cost-effectiveness of pharmacist-participated warfarin therapy management in Thailand

หน่วยงาน มหาวิทยาลัยเชียงใหม่

รายละเอียด

ชื่อเรื่อง : Cost-effectiveness of pharmacist-participated warfarin therapy management in Thailand
นักวิจัย : Saokaew S. , Permsuwan U. , Chaiyakunapruk N. , Nathisuwan S. , Sukonthasarn A. , Jeanpeerapong N.
คำค้น : -
หน่วยงาน : มหาวิทยาลัยเชียงใหม่
ผู้ร่วมงาน : -
ปีพิมพ์ : 2556
อ้างอิง : 00493848 , 10.1016/j.thromres.2013.08.019 , THBRA , http://www.scopus.com/inward/record.url?eid=2-s2.0-84885179289&partnerID=40&md5=1115a7d2f284d1287ba0f5e95bc6d187 , http://cmuir.cmu.ac.th/handle/6653943832/4211
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

Introduction Although pharmacist-participated warfarin therapy management (PWTM) is well established, the economic evaluation of PWTM is still lacking particularly in Asia-Pacific region. The objective of this study was to estimate the cost-effectiveness of PWTM in Thailand using local data where available. Methods A Markov model was used to compare lifetime costs and quality-adjusted life years (QALYs) accrued to patients receiving warfarin therapy through PWTM or usual care (UC). The model was populated with relevant information from both health care system and societal perspectives. Input data were obtained from literatures and database analyses. Incremental cost-effectiveness ratios (ICERs) were presented as year 2012 values. A base-case analysis was performed for patients at age 45 years old. Sensitivity analyses including one-way and probabilistic sensitivity analyses were constructed to determine the robustness of the findings. Results From societal perspective, PWTM and UC results in 39.5 and 38.7 QALY, respectively. Thus, PWTM increase QALY by 0.79, and increase costs by 92,491 THB (3,083 USD) compared with UC (ICER 116,468 THB [3,882.3 USD] per QALY gained). While, from health care system perspective, PWTM also results in 0.79 QALY, and increase costs by 92,788 THB (3,093 USD) compared with UC (ICER 116,842 THB [3,894.7 USD] per QALY gained). Thus, PWTM was cost-effective compared with usual care, assuming willingness-to-pay (WTP) of 150,000 THB/QALY. Results were sensitive to the discount rate and cost of clinic set-up. Conclusion Our finding suggests that PWTM is a cost-effective intervention. Policy-makers may consider our finding as part of information in their decision-making for implementing this strategy into healthcare benefit package. Further updates when additional data available are needed. © 2013 Elsevier Ltd.

บรรณานุกรม :
Saokaew S. , Permsuwan U. , Chaiyakunapruk N. , Nathisuwan S. , Sukonthasarn A. , Jeanpeerapong N. . (2556). Cost-effectiveness of pharmacist-participated warfarin therapy management in Thailand.
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Saokaew S. , Permsuwan U. , Chaiyakunapruk N. , Nathisuwan S. , Sukonthasarn A. , Jeanpeerapong N. . 2556. "Cost-effectiveness of pharmacist-participated warfarin therapy management in Thailand".
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Saokaew S. , Permsuwan U. , Chaiyakunapruk N. , Nathisuwan S. , Sukonthasarn A. , Jeanpeerapong N. . "Cost-effectiveness of pharmacist-participated warfarin therapy management in Thailand."
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2556. Print.
Saokaew S. , Permsuwan U. , Chaiyakunapruk N. , Nathisuwan S. , Sukonthasarn A. , Jeanpeerapong N. . Cost-effectiveness of pharmacist-participated warfarin therapy management in Thailand. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2556.