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Mosquito repellency of the seeds of celery (Apium graveolens L.)

หน่วยงาน มหาวิทยาลัยเชียงใหม่

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ชื่อเรื่อง : Mosquito repellency of the seeds of celery (Apium graveolens L.)
นักวิจัย : Tuetun B. , Choochote W. , Rattanachanpichai E. , Chaithong U. , Jitpakdi A. , Tippawangkosol P. , Riyong D. , Pitasawat B.
คำค้น : -
หน่วยงาน : มหาวิทยาลัยเชียงใหม่
ผู้ร่วมงาน : -
ปีพิมพ์ : 2547
อ้างอิง : 00034983 , 10.1179/000349804225003334 , 15228722 , ATMPA , http://www.scopus.com/inward/record.url?eid=2-s2.0-3142523286&partnerID=40&md5=41198936914e7ece9185836c764be724 , http://www.ncbi.nlm.nih.gov/pubmed/15228722 , http://cmuir.cmu.ac.th/handle/6653943832/4105
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

When the mosquito repellencies of four fractions of Apium graveolens seeds (one hexane, two dichloromethane and one methanolic) were investigated in the laboratory, all four were found to offer human volunteers some protection against female, adult Aedes aegypti. The hexane fraction, however, was found to exhibit the highest repellency in the laboratory, with median effective doses (ED50) and ED95 of 0.41 and 2.93 mg/cm2 skin, respectively. Only this fraction, which was also found to provide protection against mosquito bites for 3.5 h when applied, in the laboratory, at a concentration of 250 mg/ml, was then investigated for its repellency in the field and its stability. In storage, it was found to retain its repellency for at least 2 months, although significant reductions in its repellency were observed (in terms of shortened complete-protection times) after 3 months, whatever the temperature of storage (-20°C, 4°C, or room temperature). When applied to the skin of volunteers under field conditions, the hexane fraction showed strong repellent activity against a wide range of mosquito species belonging to various genera (Ae. gardnerii, Ae. lineatopennis, Armigeres subalbatus, Culex tritaeniorhynchus, Cx. vishnui group, Cx. quinquefasciatus and Mansonia uniformis). It appeared not to cause dermal irritation or any other adverse effect, either during 6 months of use or in the following 3 months of follow-up. Mosquito repellents based on extracts of Ap. graveolens seeds could be developed commercially, as an effective personal-protection measure against mosquito bites and the diseases caused by mosquito-borne pathogens.

บรรณานุกรม :
Tuetun B. , Choochote W. , Rattanachanpichai E. , Chaithong U. , Jitpakdi A. , Tippawangkosol P. , Riyong D. , Pitasawat B. . (2547). Mosquito repellency of the seeds of celery (Apium graveolens L.).
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Tuetun B. , Choochote W. , Rattanachanpichai E. , Chaithong U. , Jitpakdi A. , Tippawangkosol P. , Riyong D. , Pitasawat B. . 2547. "Mosquito repellency of the seeds of celery (Apium graveolens L.)".
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Tuetun B. , Choochote W. , Rattanachanpichai E. , Chaithong U. , Jitpakdi A. , Tippawangkosol P. , Riyong D. , Pitasawat B. . "Mosquito repellency of the seeds of celery (Apium graveolens L.)."
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2547. Print.
Tuetun B. , Choochote W. , Rattanachanpichai E. , Chaithong U. , Jitpakdi A. , Tippawangkosol P. , Riyong D. , Pitasawat B. . Mosquito repellency of the seeds of celery (Apium graveolens L.). เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2547.