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Potential use of probiotic Lactobacillus plantarum SS2 isolated from a fermented plant beverage: Safety assessment and persistence in the murine gastrointestinal tract

หน่วยงาน มหาวิทยาลัยเชียงใหม่

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ชื่อเรื่อง : Potential use of probiotic Lactobacillus plantarum SS2 isolated from a fermented plant beverage: Safety assessment and persistence in the murine gastrointestinal tract
นักวิจัย : Duangjitcharoen Y. , Kantachote D. , Ongsakul M. , Poosaran N. , Chaiyasut C.
คำค้น : -
หน่วยงาน : มหาวิทยาลัยเชียงใหม่
ผู้ร่วมงาน : -
ปีพิมพ์ : 2552
อ้างอิง : 09593993 , 10.1007/s11274-008-9894-0 , WJMBE , http://www.scopus.com/inward/record.url?eid=2-s2.0-61349178873&partnerID=40&md5=a3078ae2e90a0339788b8af2b1e1421e , http://cmuir.cmu.ac.th/handle/6653943832/604
ที่มา : -
ความเชี่ยวชาญ : -
ความสัมพันธ์ : -
ขอบเขตของเนื้อหา : -
บทคัดย่อ/คำอธิบาย :

A strain of Lactobacillus plantarum SS2 isolated from a fermented star fruit (Averrhoa carambola) beverage product in Thailand has been reported to have some probiotic properties, in vitro. In the present study, its in vivo safety and gastrointestinal survival following oral administration to mice was investigated. The acute toxicity test on ICR mice by force-feeding of a single dose of 109 and 1012 cells per mouse over 14 days after ingestion showed no adverse effects related to the normal behavior of the laboratory mouse. Although the weight gains of the dosed mice were lower than the control they were still within normal values. There were no significant differences in liver weight ratio or spleen weight index among tested mice and control mice and no evidence of bacteremia. Live SS2 cells labeled with a fluorescent dye (cFDA-SE) and administered orally at 109 cells per mouse were shown to persist in the gastrointestinal tract for 7 days. Colonies similar to the SS2 were detected in fecal samples from the test mice even though the fecal lactic acid bacterial count showed no significant difference in any mice. The strain SS2 is therefore considered to be a possible alternative choice for an inoculum to produce fermented plant beverages. © 2008 Springer Science+Business Media B.V.

บรรณานุกรม :
Duangjitcharoen Y. , Kantachote D. , Ongsakul M. , Poosaran N. , Chaiyasut C. . (2552). Potential use of probiotic Lactobacillus plantarum SS2 isolated from a fermented plant beverage: Safety assessment and persistence in the murine gastrointestinal tract.
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Duangjitcharoen Y. , Kantachote D. , Ongsakul M. , Poosaran N. , Chaiyasut C. . 2552. "Potential use of probiotic Lactobacillus plantarum SS2 isolated from a fermented plant beverage: Safety assessment and persistence in the murine gastrointestinal tract".
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ .
Duangjitcharoen Y. , Kantachote D. , Ongsakul M. , Poosaran N. , Chaiyasut C. . "Potential use of probiotic Lactobacillus plantarum SS2 isolated from a fermented plant beverage: Safety assessment and persistence in the murine gastrointestinal tract."
    เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ , 2552. Print.
Duangjitcharoen Y. , Kantachote D. , Ongsakul M. , Poosaran N. , Chaiyasut C. . Potential use of probiotic Lactobacillus plantarum SS2 isolated from a fermented plant beverage: Safety assessment and persistence in the murine gastrointestinal tract. เชียงใหม่ : มหาวิทยาลัยเชียงใหม่ ; 2552.